I've held a Glock 9mm before that felt good but I want to know if I should broaden my horizons.
A Gen 4 Glock 17 has the adjustable backstrap - no direct experience (some like, many don't), but in theory, can make it even more comfortable for larger hands (with the largest of the 3 grip sizes).
Sig P226 is another fine choice, from a fine company. Sig also has the newer P250 in the full sized configuration looks like a hoss (and more similiar in ergonomics to the Glock and M&P models than the "standard" Sig pistols). The 250 is priced fairly reasonably.
I can't recommend the Beretta 92, but is is also a popular holster gun that would be a good fit for larger hands.
If you find a gun you really like, there are options to add a wrap around grip if the grip size may be the sticking point.
Good luck with the search.
This post was edited on 1/25 at 12:02 pm