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Ebola blood test question...(sorry for another Ebola thread)

Posted on 10/16/14 at 1:57 pm
Posted by StormTiger
Norwich, England, but from TX
Member since Dec 2003
4892 posts
Posted on 10/16/14 at 1:57 pm
I haven't run across the answer to these questions...

1. How quickly would ebola show up in a blood test? (ie if people thought they had been infected, yesterday, say on a plane, how long would it take for that to show up in a blood test?)

2. How long does it take to get blood test results back for ebola?

Just seems like given the over-reaction panic this is causing, it'd be a good idea to test everyone they can as soon as possible and rule them out.

Sorry for my lack of viral understanding here.
Posted by Winkface
Member since Jul 2010
34377 posts
Posted on 10/16/14 at 1:58 pm to
Hopeful Doc will be along shortly with his essay.

But I'll take a stab...

quote:

1. How quickly would ebola show up in a blood test?
From what I understand, it is based on your viral load. The higher your viral load, the better the results of the test. Also, the higher the viral load, the more likely you are to show symptoms.


quote:

2. How long does it take to get blood test results back for ebola?
A few hours.
This post was edited on 10/16/14 at 2:02 pm
Posted by Traffic Circle
Down the Rabbit Hole
Member since Nov 2013
4231 posts
Posted on 10/16/14 at 2:00 pm to
Stick a fork in it. Ebola is done. All over. Finished.

Moving on to the next crisis.
Posted by TigerBait1127
Houston
Member since Jun 2005
47336 posts
Posted on 10/16/14 at 2:00 pm to


quote:

1. How quickly would ebola show up in a blood test? (ie if people thought they had been infected, yesterday, say on a plane, how long would it take for that to show up in a blood test?)



quote:

Just seems like given the over-reaction panic this is causing, it'd be a good idea to test everyone they can as soon as possible and rule them out.



Where are you going with this?
Posted by lsunurse
Member since Dec 2005
128950 posts
Posted on 10/16/14 at 2:00 pm to
quote:

it'd be a good idea to test everyone



That sounds expensive
Posted by StormTiger
Norwich, England, but from TX
Member since Dec 2003
4892 posts
Posted on 10/16/14 at 2:04 pm to
quote:

That sounds expensive


more expensive then quarantine?
Posted by lsunurse
Member since Dec 2005
128950 posts
Posted on 10/16/14 at 2:04 pm to
I just meant...clarify who you mean by "everyone"
Posted by StormTiger
Norwich, England, but from TX
Member since Dec 2003
4892 posts
Posted on 10/16/14 at 2:06 pm to
quote:

I just meant...clarify who you mean by "everyone"


every nurse that was at that hospital and treated the guy?

everyone in his apartment before he was put in the hospital?

If it showed up pretty much right away (which is what I don't know), wouldn't that have been a cost worth paying for?
Posted by Hopeful Doc
Member since Sep 2010
14942 posts
Posted on 10/16/14 at 2:06 pm to
quote:

Hopeful Doc will be along shortly with his essay.



quote:

1. How quickly would ebola show up in a blood test? (ie if people thought they had been infected, yesterday, say on a plane, how long would it take for that to show up in a blood test?)


Test can be negative for the first 3-5 days of the patient showing symptoms.

ETA: The patient is actually infected 2-21 days before showing symptoms though. It's possibly negative for up to the first 5 days of the patient showing symptoms, so, to answer your question more accurately, 2-26 days after infection.

quote:

2. How long does it take to get blood test results back for ebola?


PCR tests usually take several hours at the fastest, a few days at slowest. Probably 12-36 hours, if I'm guessing.

quote:

Just seems like given the over-reaction panic this is causing, it'd be a good idea to test everyone they can as soon as possible and rule them out.


This is a very expensive test, and it will be negative in every single person that does not show symptoms. This would be a colossal waste of money. It's what's referred to as a "confirmatory" test. What we want/need/would be what you're describing would be a good "screening" test. There is currently no good screening test for Ebola. There are several in the works, and at least one by the US Navy that will be faster but likely less sensitive.
This post was edited on 10/16/14 at 2:08 pm
Posted by StormTiger
Norwich, England, but from TX
Member since Dec 2003
4892 posts
Posted on 10/16/14 at 2:09 pm to
quote:

This is a very expensive test, and it will be negative in every single person that does not show symptoms. This would be a colossal waste of money. It's what's referred to as a "confirmatory" test. What we want/need/would be what you're describing would be a good "screening" test. There is currently no good screening test for Ebola. There are several in the works, and at least one by the US Navy that will be faster but likely less sensitive.


/end thread.

Thanks for the definitive answer.
Posted by CadesCove
Mounting the Woman
Member since Oct 2006
40828 posts
Posted on 10/16/14 at 2:13 pm to
Why haven't they whipped up more batches of the "experimental" drug that they gave the two missionaries in Atlanta? Or have they, and I just haven't heard about it?
Posted by GrammarKnotsi
Member since Feb 2013
9315 posts
Posted on 10/16/14 at 2:16 pm to
quote:

“The current test requires that you take a tube of blood from a person’s arm, first of all that’s a risk for the person drawing the blood. What our test allows you to do is just use a finger prick; very safe device, small drop of blood, you can put a band-aid over it. You don’t have to expose the person drawing the blood to the risk of a needle or a needle stick. Then you take that small drop of blood, put it on this device, 15 minutes later you have a result,” explains Dr. Garry.
Posted by Hopeful Doc
Member since Sep 2010
14942 posts
Posted on 10/16/14 at 2:31 pm to
quote:

Why haven't they whipped up more batches of the "experimental" drug that they gave the two missionaries in Atlanta? Or have they, and I just haven't heard about it?



That's on the company itself. Every patient treated in the US has received some form of experimental drug. There is zero data on any of them to suggest that it helped, harmed, or had no effect on any of the patients who have received the drugs to date.
Posted by Winkface
Member since Jul 2010
34377 posts
Posted on 10/16/14 at 2:38 pm to
quote:

What is being done to accelerate ZMappTM production?
Mapp and KBP are working with the U.S. government to accelerate scaled up
production. The work to date has been funded by grants and contracts that were only
sufficient to produce doses for animal safety and efficacy testing. The present epidemic
has changed the picture dramatically, and additional resources are being brought to bear
on scaling up. It is important to note that the emergency use of an experimental
medicine is a highly unusual situation. As a consequence global high-level discussions
concerning the policy, ethical, and medical implications of this exceptional situation have
been initiated.
Posted by CadesCove
Mounting the Woman
Member since Oct 2006
40828 posts
Posted on 10/16/14 at 2:41 pm to
quote:

There is zero data on any of them to suggest that it helped, harmed, or had no effect on any of the patients who have received the drugs to date.


Didn't the two in Atlanta live after they got it? And the guy in Dallas died after not getting it. I feel like it might make a difference.
Posted by Ducyborg
Denver, CO
Member since Apr 2012
1191 posts
Posted on 10/16/14 at 2:47 pm to
Better question is if you had ebola and a vampire sucked your blood, would the vampire get ebola and would it kill said vampire?
Posted by Hopeful Doc
Member since Sep 2010
14942 posts
Posted on 10/16/14 at 2:50 pm to
quote:

Didn't the two in Atlanta live after they got it? And the guy in Dallas died after not getting it.



Since this outbreak, ZMapp has been used in:
2 Americans who recovered
1 75 year old Spanish priest who died after receiving it (1)
3 Liberians, one died (2)
1 British nurse who lived

2/7 who have received ZMapp died.

One received Brincidofovir and died.

quote:

I feel like it might make a difference

It might. To say so definitively is to be highly swayed by a very unconvincing sample size which also doesn't mention when during the infectious process the patients began aggressive supportive therapy as well as antiviral therapy.
Posted by CadesCove
Mounting the Woman
Member since Oct 2006
40828 posts
Posted on 10/16/14 at 2:56 pm to
And it was made in the good ol' USofA with KY tobacco plants, correct? So Michael Bloomburg can go frick himself.
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