I worry more about rebounding with that lineup. We will get killed on the boards. Very few second chances for us on offense, and way too many second chances for the opposing team.
This link talks about the Spurs and Celtics defenses. Specifically, how the Celtics had one of the best defenses in the league in 2011-2012 but were only 20th in DReb. If anything, Anderson's lack of rim protecting abilities could be the liability. Perhaps that can be overcome if he becomes great at anticipating and rotating. LINK
Plus, Quail Man said something in another thread about pace and it's effect on defenses that got me thinking about this article I read a few years ago. Didn't remember that Rohan wrote it, but it's quite interesting. It breaks Pace down further into Offensive and Defensive Speed. LINK
Not sure if there's a path to follow here. But the data does seem to support the idea that a team can play fast on offense (Chicago/Orlando both around 100 Speed Index) and still be able to dominate defensively.