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Olmesartan HCTZ and fatigue

Posted on 5/11/24 at 12:41 pm
Posted by BatonRougeBuckeye
Baton Rouge, LA
Member since Aug 2013
1794 posts
Posted on 5/11/24 at 12:41 pm
Started this in January with no real problems but since it’s started getting hot I cannot do anything in the heat without extreme fatigue. Previous to this it’s not been a problem. I’m 57 and know I can’t do what I did at 21 but wondering if this is the issue and if anyone else has had a similar experience.
Posted by DrDenim
By the airport
Member since Sep 2022
523 posts
Posted on 5/11/24 at 2:23 pm to
I do not, but if I were you I'd talk to my doctor. Do you have a way to check your blood pressure when you feel this way? You may need to plan ahead when you intend to be in the heat and supplement with some extra electrolytes. BUT...seriously...and this is coming from an icu nurse, my work life is full of dealing with people that made understandable mistakes with their health and medications, they didn't know what they didn't know, until too late. Don't mess around in the heat until you know whats going on with your BP. We nurses identify several "different" kinds of seasons from the traditional Spring/Summer/Fall/Winter, of course we have "flu season" but for now we are coming into (or it's already begun, depending on where you live and how hot it is) "Old Guys Who Are Gonna Have Their First Heart Attack While Working Out In The Heat Season". It's a big season unfortunately.

Now....you aren't old, really, but you are on an "old guy med" so I'd schedule that appt and until then take it easy in the heat and be extra aggressive with hydration and electrolytes. If you're already doing that, I don't know what to say.
Posted by BatonRougeBuckeye
Baton Rouge, LA
Member since Aug 2013
1794 posts
Posted on 5/11/24 at 2:34 pm to
quote:

I do not, but if I were you I'd talk to my doctor. Do you have a way to check your blood pressure when you feel this way? You may need to plan ahead when you intend to be in the heat and supplement with some extra electrolytes. BUT...seriously...and this is coming from an icu nurse, my work life is full of dealing with people that made understandable mistakes with their health and medications, they didn't know what they didn't know, until too late. Don't mess around in the heat until you know whats going on with your BP. We nurses identify several "different" kinds of seasons from the traditional Spring/Summer/Fall/Winter, of course we have "flu season" but for now we are coming into (or it's already begun, depending on where you live and how hot it is) "Old Guys Who Are Gonna Have Their First Heart Attack While Working Out In The Heat Season". It's a big season unfortunately. Now....you aren't old, really, but you are on an "old guy med" so I'd schedule that appt and until then take it easy in the heat and be extra aggressive with hydration and electrolytes. If you're already doing that, I don't know what to say.


Thank you for the info. I too am concerned about overdoing it in the heat in south Louisiana. I’m taking your advice. Thank you.
Posted by La Place Mike
West Florida Republic
Member since Jan 2004
28838 posts
Posted on 5/11/24 at 2:59 pm to
I started it 4 weeks ago and the first weekend my BP dropped while I was out and about. It wasn't hot but extremely sunny. So I cut my dose in half and the same thing happened the very next weekend while out and about. Again it wasn't hot. So I cut the dose to a quarter and my BP stayed in the 120/80 range. So fast forward to this week. My BP has gone up. The difference between this week and last week is I was taking a K2 supplement. I am wondering if K2 had an affect on the medication and made my BP drop.

I was prescribed 20 mg. I am glad you started this thread OP. I was going to start one.

ETA. I have noticed that I do get fatigued sooner doing workouts and yard work.

Update. BP dropped again today. All ways happens on a Saturday.
This post was edited on 5/11/24 at 6:01 pm
Posted by Lawyered
The Sip
Member since Oct 2016
29459 posts
Posted on 5/12/24 at 10:49 am to
quote:

ETA. I have noticed that I do get fatigued sooner doing workouts and yard work.


Yall gotta make sure you’re staying hydrated especially when you’re outside

The HCTZ part of the combo pill is the diuretic so it’s pulling off water and sodium and potassium

Posted by MemphisGuy
Member since Nov 2023
3425 posts
Posted on 5/12/24 at 2:05 pm to
quote:

BP dropped while I was out and about.

Define "dropped". Did you take your BP? Or could you just tell it was dropping? How much did it drop?
Posted by La Place Mike
West Florida Republic
Member since Jan 2004
28838 posts
Posted on 5/13/24 at 1:44 pm to
quote:

Define "dropped". Did you take your BP?


Yes, 91/65.
Posted by La Place Mike
West Florida Republic
Member since Jan 2004
28838 posts
Posted on 5/13/24 at 1:45 pm to
quote:

HCTZ


I am taking Olmesartan without the HCTZ.
Posted by DrDenim
By the airport
Member since Sep 2022
523 posts
Posted on 5/13/24 at 6:13 pm to
quote:

Yes, 91/65.


If this is the drop, where is your baseline?
Posted by La Place Mike
West Florida Republic
Member since Jan 2004
28838 posts
Posted on 5/13/24 at 9:48 pm to
120s/over high 70s.
Posted by LemmyLives
Texas
Member since Mar 2019
6544 posts
Posted on 5/13/24 at 11:30 pm to
Get an Omron brand blood pressure monitor from Sam's ($50.) Download the app. You can just show your cardiologist whatever was measured and when with almost no effort.

I just started on a diuretic a week ago, but if my pee is clear, I'm drinking enough. If it's not, I'm not. I was put on HCTZ for a few days by the ER, and the cardio switched me to chlorthalidone seems to work *far* better in terms of diuretic effects. I won't go any further down that route here, it's a family board!

I defer to the nurse in the thread, obviously, but there was a stage 10 years ago where I simply could not drink enough water. By that, I mean I would drink near a gallon of water in 45 minutes when it was hot (while working out, driving to the airport, etc.) I've always had the tendency to dehydrate easier than most because of how I sweat, but (I was in my early 30s when this was suggested, and I didn't have HBP yet) a nurse/trainer suggested a take a pinch of sea salt and dump it it in the 32 ish ounce water bottle, to increase the efficacy of how my body processed water.

I use Hydralyte every other day or so, but very weakened. It calls for one packet in 8-16oz of water, but I use half a packet in a 30 oz mug of weak unsweetened iced tea (citrus flavors work nicely in tea.)

Funny dehydration story from two weeks ago... They pumped me full of two bags of lactated ringers in the ER over about four hours. Discharged me around 7pm. Walking back to my truck, it all seemed to hit my bladder at once, but I was on the back side of the hospital where everything seemed to be badge access only. I had to piss in the parking garage, and it hit me *fast,* but the garage was mostly empty by then, so I didn't have to pee on anyone's car. Enjoy my misfortune; I had the discharge paperwork in one hand, with nowhere to put it, it could have been close to a Mr. Bean sketch I needed to pee so ridiculously badly, with almost no warning (and I mean, the situation escalated greatly over the course of 30 yards.) Getting old is awesome, am I right?
Posted by DrDenim
By the airport
Member since Sep 2022
523 posts
Posted on 5/14/24 at 12:51 am to
I would have demanded a foley catheter.

Mike, that's a pretty big swing down, you'll definitely feel that. I'm sure you're monitoring your BP, but I don't know what schedule you're keeping with that. I would check it first thing upon waking every day, take your med at the same time everyday (and be really strict, set an alarm on your phone or watch and be consistent, this helps keep drug concentration levels consistent), and if you can check your BP again before you engage in any activity that's good too. Sometime it's a pain in the arse to get dialed in with BP meds, sometimes it's a cakewalk. If you have to go back to the cardio to get something changed, it's best to be armed with a blood pressure log, with time/date, and also comments such as "after a meal" "before bedime" "before mowing the grass" "after mowing the grass, hot day" etc. You probably know all of that, but just in case.

Also, I second Lemmy's comment, and to anyone else, you don't have to go full Pedialyte/Gatorade, but adding salt to your water is a wise move in the warmer months, you can mask the taste with a little lemon/lime juice, or something like Crystal Lite powder or something like it. LMNT packets are a good option I've heard, but I've never used them.
Posted by BatonRougeBuckeye
Baton Rouge, LA
Member since Aug 2013
1794 posts
Posted on 5/14/24 at 5:30 am to
As the OP I thought Id relay info received from my doctor yesterday. Agreed that my BP was too low. Originally 130/90 and the Olmesartan and HCT brought it down to 105/75 which seemed fine. However now that the hot weather is here the HCT dehydrates me too much and my pressure was bottoming out at 85/55. Even in his office yesterday after a day of no meds it was 100/70 which he felt was too low.

he has switched me to Olmesartan without the HCT. We'll see what happens.
Also I do have an omron BP machine.
Posted by DrDenim
By the airport
Member since Sep 2022
523 posts
Posted on 5/14/24 at 11:12 am to
Glad you got it worked out. It's too early in the season to be having these troubles.

I don't live in the deep South, I live in northeastern Oklahoma, but it gets hot here too. However, I lived in Houston from 2017-2021, and that felt like dangerous heat that just dragged on for months. Those long summers and the humid heat are tough for people on BP meds unless you just hide inside 24/7. It would be easy to say "Just stay super-hydrated all the time, drink 2 gallons of pickle juice a day", but that can cause problems too. Good luck. I'm an Omron man too, that's the only brand of home blood pressure machine I'll use, some people don't trust them, but I have a manual cuff and a stethescope and my Omron is consistent with that. They work.
Posted by La Place Mike
West Florida Republic
Member since Jan 2004
28838 posts
Posted on 5/14/24 at 6:52 pm to
O could definitely feel it. It was lower than that the other times. I take the medicine every morning and try to take BP every morning for now it seems like 5 mg is working. I see a cardiologist next week and will see what he says.
Posted by LemmyLives
Texas
Member since Mar 2019
6544 posts
Posted on 5/15/24 at 2:09 am to
quote:

I would have demanded a foley catheter


Well, while I was in the ER, I heard that a bus was inbound with a code blue, and they coded again after arrival about 60-90 minutes later. I knew I wouldn't be seeing anyone for an extended period of time after each announcement. They didn't document the diuretic or BP meds they gave me via IV, only the Atavan (I started subconsciously panicking as people continued to not tell me anything, when I see the 242/130 BP reading, etc.) They gave me the unsigned discharge paperwork in my discharge folder, etc. On the plus side, there is a level that your BP reaches that you don't wait in the ER, lol.

Mike, there's an app called "Medisafe," and the alarms will annoy the hell out of you. But you'll be on time. Depending on your water, the pinch of salt (West Houston is hard water, but I mean a pinch, not a 1/4 tsp) {edit} may just make the water taste softer.

And Mike, three days later, I had two beers at the pub, and was leaving, and a mid-60s dude ended up face down on the bar with his wife calling his name trying to get him to respond. He'd had a little over a beer, ended up with a couple of compressions, and when I saw him in my parking garage in the passenger seat a few days later, there is clearly slack jaw, inability to control facial expressions appropriately, he's not great. Don't ignore side effects.

For your cringe/laughter, DrDenim, his wife said she could go get her keys to drive him to the ER (we live in the same complex 80 yards away), in the middle of me asking if he was breathing (I was holding him up, there were not enough people for me to get him on the ground safely.) F no. Amboolance!

After he got the compressions and started talking, they were wheeling him out. His wife tried to close the tab for $15 worth of 3 drinks. It was surreal, her shock response was odd.
This post was edited on 5/15/24 at 2:10 am
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